Grand Theft Auto series passes 220 million sales worldwide
According to data on Wikipedia, Mario as a franchise currently sits at number one with 509 million sales. Pokémon is number two with 297 million.
After Grand Theft Auto, the next largest game franchise is Call of Duty, which Activision listed as 175 million back in March.
Sales of Grand Theft Auto V are likely to continue going strong since there still updates in the works, like the Rockstar Editor feature coming to PS4 and Xbox One with the game's next patch. However, Take-Two offered a statement of "no comment" when last asked about the status of story-based DLC content for GTA V.